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Some sea slugs can shed nearly their entire body, including the heart, and regenerate a new one from the surviving head. A remarkable study reveals how this process unfolds and explores whether stolen chloroplasts and internal parasites hold clues to its purpose.
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A typical honey bee drone has a mother but no father because it develops from an unfertilized egg and carries one chromosome set. Here is how that system works, why csd complicates the simple rule, and what it means for bee families.
Get the idea →Laboratory-made mRNA could trigger innate immune alarm signals. Karikó, Weissman and colleagues showed that changing the chemistry of RNA nucleosides could dramatically alter how immune cells recognized the molecule.
Get the idea →A pill does not search for the painful organ. After absorption, drug molecules circulate through the body, enter accessible tissues, interact with molecular targets, and are eventually metabolized and eliminated.
Get the idea →Different cells in the same woman can use different parental X chromosomes. X inactivation silences most of one X early in development, creating a lifelong cellular mosaic.
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01An analysis of 1,640 methylomes from 894 dogs found that larger dogs age faster at the molecular level. Size-related changes were especially pronounced at transposable elements, including LINE1 sequences.
02Chronically stimulated CD8+ T cells can burn through energy by sustaining intense protein production. In cell and mouse models, MEK inhibition lowered this demand and helped preserve a longer-lived, self-renewing T cell state.
03Artificial intelligence can now estimate a woman's likelihood of developing breast cancer within five years using an existing mammogram. As an FDA-authorized tool becomes available across the United States, clinical evidence reveals both the potential and the limitations of image-based risk prediction.
04Can water retain a trace of words, emotions, or substances that are no longer present? We examine what physicists actually mean by water “memory,” what the 50-femtosecond result shows, and why it does not validate popular claims.
05Normal tissues from different people showed striking variation in somatic mutation burden even after accounting for age. The findings raise the possibility that some individuals accumulate mutations faster than others.
06A bacterial metabolite produced in the gut altered immune-cell behavior and experimental stroke severity in mice. Human data pointed in the same direction, but remained observational and did not establish the same causal pathway.
07The active form of vitamin D reduced viability, mitochondrial potential and migration in A375 melanoma cells, while SK-MEL-28 cells showed little response. The contrast highlights substantial biological heterogeneity within melanoma.
08A Nature Aging study traces one molecular route from aerobic exercise to aging cartilage. Exercise altered extracellular-vesicle cargo, with microRNA-29 helping restore healthier chondrocyte features through the KL/α-Klotho pathway.
09An iron-activated enzyme drove energy-wasting changes in adipose tissue in pancreatic cancer models. Removing MsrA reduced fat and muscle wasting and prolonged survival in tumor-bearing mice.
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